Congratulations Dr. Doyle!

Our wonderful Shelby Doyle became the second graduate student in the lab from the Department of Biological Engineering at MIT to successfully defend her thesis, just in time for the well-earned holiday break in December of 2019!

Dr. Doyle’s thesis, entitled Modulating Oncogenic Transcription with Small Molecules, was a tour de force and emphasized various strategies to tackle AR-driven transcriptional programs. Keep an eye out for upcoming publications related to her thesis work around a selective CDK9 inhibitor and a chemical probe of the OXPHOS pathway! The lab is so proud of your accomplishments!

Shelby and Family relaxing after a job well done!

Taking a Moonshot at a rare pediatric cancer

The Koehler lab is proud to join a collaborative team involving investigators at Duke University, the Broad Institute, the National Cancer Institute, and the University of Zurich with the goal of developing tools to inform therapeutics for fusion-positive alveolar rhabsomyosarcoma. This effort is generously funded via the NCI Cancer Moonshot Initiative. You can read more about our efforts here: https://news.mit.edu/2019/taking-moonshot-rare-childhood-cancer-arms-1120

Yulong Su named a Convergence Scholar!

Congratulations to Yulong Su for being named a Convergence Scholar for the MIT Center for Precision Cancer Medicine. Yulong’s work strives to address oncogenic transcriptional programs in a variety of cancer types, emphasizing strategies to control the protein levels of oncogenic factors such as MYC. Read more here: https://ki.mit.edu/news/2019/introducing-2019-2020-convergence-scholars

MIT CPCM 2019-2020 ConVergence Scholars